Acute closed-angle glaucoma, mostly seen in elderly people over 50 years old, is often caused by acute major glaucoma attacks after emotional excitement and overexertion. In addition to ocular symptoms, it is often accompanied by systemic manifestations such as nausea, vomiting and headache. Patients may ignore the ocular symptoms and often consult gastroenterology or neurology, thus delaying treatment. Note: Although glaucoma is an irreversible and blinding eye disease, the condition can be effectively controlled if it is detected and treated early. Therefore, it is important to know some general knowledge about glaucoma so that you can raise your awareness of prevention in your daily life. When you encounter headache and nausea, if it is accompanied by eye manifestations such as eye redness, photophobia, eye pain and blurred vision, you must be alert! While consulting internal medicine, visit the ophthalmology department as early as possible to rule out glaucoma. The common clinical manifestations of acute angle-closure glaucoma: 1, the attack is often preceded by mental and emotional triggers or had excessive eye use in dark places; 2, rainbow vision” (i.e., when looking at lights, there is a rainbow-like halo); 3, a sharp decline in vision, severe cases have only the immediate index, or even only light perception; 3, sudden and severe eye distension, reflex headache, malignant, vomiting and other symptoms. A small number of patients may have diarrhea; 4, the eye pressure is elevated, even “hard as a stone”; 5, the eye is red (i.e., conjunctival congestion), corneal edema cloudy, pupil dilated, as shown in the figure.