Rectal drug delivery is a treatment method in which the drug is delivered from the anus to the rectum and then absorbed and utilized directly by the rectal mucosa. Its main characteristics are fast onset of action and low side effects, which are especially suitable for adults and children who have difficulties in taking drugs orally, as well as some patients with anal and urinary system diseases. One of the common methods of rectal drug delivery is rectal drip method, suppository plugging method and reserved enema method. The rectal drip method refers to the infusion of herbal medicines into the rectal drip catheter connected to the pvc and administered by drip. Suppository plugging method refers to the formation of suppositories of drugs through the anus directly into the rectum of the anal canal, and keep the drug does not leak out to make the drug effective. Retained enema method is the direct infusion of herbal medicine through the anus, and can be supplemented by the use of anal plugs, so that the drug is retained with the rectum and colon, so that the intestinal mucosa quickly absorbs the active ingredients in the drug. The most common rectal drug delivery method for adults is the suppository plug method.