The difference between lumbar muscle strain and nephropathic low back pain is in the aspects of etiology, symptoms and treatment principles. 1. Etiology: lumbar muscle strain is usually caused by long-term lifting heavy objects, sedentary standing and other factors. Nephropathy low back pain may be caused by urinary tract infection that causes low back pain, or the presence of glomerulonephritis, renal tumors and so on. 2. Symptoms: The main symptom of lumbar strain is lumbar or lumbosacral pain, which is recurring and will change with the season or fatigue level. Nephropathy back pain usually has urinary changes, such as increased nocturia, urinary urgency, hematuria and other bladder irritation, and also renal area percussion pain. 3. Treatment principle: Lumbar muscle strain is mostly treated with comprehensive treatment methods, such as taking painkillers, low back muscle training and other methods. Nephropathy back pain adopts different treatments according to different causes, nephritis can be treated with anti-infection, chronic renal failure can be treated with hemodialysis, and uremia can be treated with surgery such as renal transplantation. The appearance of lumbar muscle strain and nephropathic low back pain and other diseases, timely to the regular hospital examination, according to the cause of targeted treatment, to avoid delays in the condition, resulting in serious consequences.