Some eye drops can cause local irritation to the eyes, resulting in soreness and pain. Most of these conditions are seen in quinolone drops, such as ofloxacin drops, lomefloxacin drops, and gatifloxacin drops. Mild eye soreness and pain will not have a serious effect on eye medication and most of these symptoms will improve after a few days of continued use of the drops. If there is severe soreness and pain, accompanied by bloodshot, red and swollen eyes, there is an allergy to this type of medication, so it is necessary to stop using it immediately and suggest replacing it with other types of eye drops, such as tobramycin eye drops, chloramphenicol eye drops, etc. Most of them will get better after replacing them. For severe allergy, you may need to use hormonal eye drops in combination.