If a thorn is lodged in your hand, you can pick it out by yourself using sterilized tweezers or the like if the lodging is shallow. If the splinter is deeper, you will need to go to the hospital to have the wound enlarged and the splinter removed. If the splinter is only lodged in the superficial layer of the hand, you can pick out the splinter on your own using sterile needles, tweezers and other tools. Then disinfect the area with povidone-iodine to avoid infection. Erythromycin ointment can also be applied to prevent infection. If the splinter is lodged deep in the hand, swelling, pain is obvious and there is active bleeding, then you should go to the hospital to seek medical help. Under local anesthesia, the doctor will enlarge the wound and remove the foreign body. Then the wound will be sterilized and bandaged. In addition, antibiotics such as amoxicillin can be taken as prescribed to fight infection. All stab wounds deep into the hand should be injected with tetanus antitoxin to prevent tetanus infection. In conclusion, for thorns lodged in the hand, different treatments should be taken according to the depth of the thorns lodged in.