Spontaneous pneumothorax is formed when a pulmonary blister ruptures on its own and air from the lungs and bronchi enters the pleural cavity. It is usually seen in young and middle-aged men or in patients who have a combination of chronic bronchitis, emphysema, or tuberculosis. What to do about ruptured pulmonary blisters needs to be analyzed on a case-by-case basis. If the volume of spontaneous pneumothorax is less than one-fifth of the volume of the chest cavity, the clinical symptoms are not obvious, so it can be observed first, and there is no need for pumping or closed drainage of the chest cavity for the time being. Recurrent small spontaneous pneumothorax can also be treated surgically to avoid further expansion of the pulmonary blister. Large pneumothorax must be treated by thoracentesis or closed chest drainage to drain the gas from the chest cavity to the outside of the body as soon as possible, to relieve the pressure of the gas on the lung and mediastinum, and to promote the lung to reopen as soon as possible. For patients with large pneumothorax, they must be sent to hospital for treatment as soon as possible, and the above treatment methods need to be operated by professionals only. If a tension pneumothorax is suspected, resuscitation measures should be prepared as soon as possible. To sum up, ruptured pulmonary blisters are not serious, most of them are considered conservative treatment with puncture if necessary, and more serious cases may require closed chest drainage.