One year after glioma surgery, the softness of lower limbs of both legs is considered to be related to the recurrence of glioma, malnutrition, decline of cardiopulmonary function and other factors. 1. Recurrence of glioma: for some patients, after one year of glioma surgery, the softness of walking legs and lower limbs can not be excluded, which is related to the local recurrence factors, and this kind of patients are often accompanied by nausea and vomiting, dizziness and headache, blurred vision and other related symptoms, which can be further examined and clarified. 2. Malnutrition: This is also the phenomenon that causes patients to walk the lower limbs of the legs soft. The symptoms may be due to malnutrition, insufficient dietary intake and lack of energy support. 3. Decline of cardiopulmonary function: patients may stay in bed for a long time and lack of exercise after surgery, which leads to the decline of cardiopulmonary function, and the weakness of lower limbs will appear gradually. The phenomenon of softness of lower limbs of walking legs one year after glioma surgery may also have other reasons, such as hydrocephalus, chemotherapy leading to peripheral neuropathy, if necessary, need to cooperate with doctors to do further examination, and then do the corresponding treatment and therapy.