Liver insufficiency and liver injury have certain differences in etiology and degree of lesions. 1. Different etiology: Liver insufficiency refers to the deterioration of liver function on the basis of acute or chronic liver diseases, and the damage of liver cells of the patients is more serious, and the detection of liver function shows that the level of transaminase is obviously increased, and the level of bilirubin can also be changed. Abnormalities in liver function can also occur under physiological conditions, such as sleep deprivation and excessive anxiety and stress, which can also lead to increased levels of aminotransferases. 2. Degree of lesion: the degree of lesion of liver insufficiency is more serious, patients can have protein synthesis disorder, metabolism disorder, detoxification disorder, etc., and sometimes the condition is irreversible; whereas the abnormal physiological condition of liver function will be improved quickly after lifting the triggers. Pathologic conditions such as fatty liver and alcoholic hepatitis will be reversed after active treatment. For liver insufficiency and liver function abnormalities, it is recommended to consult the gastroenterology department of a regular hospital.