Pathologic examination is required after submucosal fibroid removal. Most uterine fibroids are benign tumors, consisting of smooth muscle and connective tissue. However, uterine smooth muscle tumors can present with cystic degeneration, red degeneration, and sarcomatoid degeneration. Most fibroids that develop sarcomatoid degeneration start from the center of the fibroid and spread to the surrounding area, and are more malignant. Pathologic examination is needed to rule out sarcomatoid degeneration of uterine fibroids after myomectomy. In perimenopausal women, uterine fibroids may be combined with endometrial cancer, and pathological examination is needed to exclude endometrial cancer after submucosal fibroidectomy. Endogenous cervical cancer and submucosal fibroids are not easy to distinguish, and need to be clearly diagnosed by pathologic examination to avoid misdiagnosis and delay. Larger endometrial polyps may be confused with submucosal fibroids and need pathologic examination to make a clear diagnosis. After removal of submucosal fibroids, it is recommended to have regular follow-up examinations under the guidance of a doctor. If you have any other questions, it is recommended that you consult a medical professional for guidance.