Itchy rash can be cured with topical medications such as glycerite lotion and systemic medications such as anti-allergy drugs and glucocorticoids, etc. Patients can follow the doctor’s instructions for medication. 1. Topical medication: commonly used medications include mometasone furoate cream with anti-itching effect; ice camphor eucalyptus fluorescent easy cream for nodular itchy rash; compound tretinoin acetate solution with anti-inflammatory, anti-allergic, exfoliation effect, which is effective for nodular itchy rash. 2. Systemic medication: anti-allergic drugs can be used in combination or alternately with two or more antihistamines, such as Epinastine hydrochloride tablets, Olopatadine hydrochloride tablets; refractory patients, short-term oral glucocorticosteroids such as prednisone, methylprednisolone and other medications. The above medication should follow the doctor’s instructions. It is recommended that patients with itchy rash go to the hospital in a timely manner and receive standardized treatment under the guidance of a doctor.