Itchy nose, stuffy nose, endless sneezing and inexhaustible nasal mucus make people restless. Although it is autumn, the weather in Guangzhou is still hot, and environmental factors such as dust, pollen and air conditioning make allergic rhinitis more likely. Zhang Guanping, a professor of otolaryngology and head and neck surgery at the Sixth Hospital of Sun Yat-sen University, said allergic rhinitis itself is not a serious disease, but it can significantly affect the quality of life of patients. If drug treatment is ineffective, recurrent, persistent rhinitis or accompanied by asthma, sublingual drug desensitization treatment may achieve good results. For intermittent episodes of allergic rhinitis, medication can effectively control the symptoms. According to Zhang Guanping, many patients only use medication when they are ill and stop taking it once their symptoms are relieved, resulting in allergic rhinitis that is sometimes good and sometimes bad. Therefore, a full course of treatment should be applied to control intermittent allergic rhinitis attacks. (1) For perennial allergic rhinitis, treatment should be continued for 1-2 months for each attack, and some patients even need to be treated for half a year; (2) For seasonal allergic rhinitis, medication should be administered 2-3 weeks in advance. After the season, medication should not be stopped immediately, but continued for about two weeks. If the effect of medication is poor, recurrent, persistent rhinitis or accompanied by asthma, desensitization treatment can be tried. Zhang Guanping said that before conducting desensitization treatment, allergen testing is first performed to determine what the patient is allergic to. In clinical practice, the skin prick test is generally used to accurately determine the patient’s allergens. This is the quickest and easiest way to detect allergens, as the skin prick is almost painless to the subject. After the allergen is identified, desensitization treatment can be performed according to the allergen. Currently, there are two clinical desensitization methods: subcutaneous injection and sublingual administration, the former of which must be done in a hospital, while the latter can be done by simply placing drops of the drug under the tongue at regular intervals. The sublingual method is easier and better than the injectable desensitization therapy, so it is more acceptable to younger patients with allergic rhinitis.