Common side effects of disodium pamidronate include asymptomatic hypocalcemia and fever, while rare side effects include flu-like symptoms such as cough and sore throat. Pamidronate disodium is a calcium modifying drug, mainly used for hypercalcemia complicated by malignant tumors and bone pain caused by osteolytic cancer metastasis. The most common side effects of disodium pamidronate include asymptomatic hypocalcemia and fever, which usually occurs within 48 hours after the drug is administered, and the patient’s body temperature will increase by 1~2°C, which can usually subside on its own. The less common side effects of the drug are cough, sore throat and flu-like symptoms. There may be pain, redness, swelling, and itching of the skin at the site of the injection. The drug passes into breast milk and should be used with caution in lactating women. Secondly, the drug may affect bone growth and is generally contraindicated in infants and young children. The use of the drug is prohibited for those who are sensitive to the drug. The specific use of the drug should be under the supervision of a doctor.