Premature gonadal development in girls usually refers to the appearance of secondary sexual characteristics before the age of 8 years, and can be seen in both central and peripheral precocious puberty, with intervention depending on the cause, e.g., central precocious puberty due to hypothalamic space-occupying lesions requires surgical treatment. Premature gonadal development in girls, which refers to the appearance of secondary sexual characteristics before the age of 8 years, is often considered to be precocious puberty, and can lead to premature skeletal fusion, which in turn affects height. It can also be seen in central precocious puberty (including idiopathic precocious puberty, secondary precocious puberty, etc.) and peripheral precocious puberty (including gonadal tumors or exogenous drug-induced), and interventions need to be tailored to the cause of the disease. In children with idiopathic precocious puberty, gonadotropin-releasing hormone analogs, such as treprostinil or leuprolide, should be used under physician supervision. Hypothalamic malformations and cysts can cause central precocious puberty, and gonadal tumors such as luteinomas and teratomas can cause peripheral precocious puberty, which may require surgical intervention. Children with primary hypothyroidism may develop central precocious puberty, and thyroid preparations (e.g., levothyroxine sodium tablets) should be given to correct thyroid function. Exogenous drugs, such as hormone-containing drugs, can cause peripheral precocious puberty and should be avoided. All of the above medications should be used under the supervision of a physician, and it is recommended to actively consult a specialist for evaluation and intervention to determine the cause of the disease.