Creatinine 147μmol/L is not necessarily nephritis. When creatinine is elevated, it may be caused by physiological factors or pathologic factors such as nephritis, urinary tract infections, diabetic nephropathy, hypertensive renal damage. 1. Physiological factors: when consuming too much meat, or recent increase in exercise, the protein metabolism in the body increases, it may be manifested in increased creatinine in the blood, which is a normal phenomenon. 2. Pathological factors: when the kidneys have glomerulonephritis, urinary tract infection, diabetic nephropathy, hypertension and other diseases, and develop to renal insufficiency, the efficiency of the kidneys in removing creatinine from the body will be reduced, and the creatinine value will be increased. It is necessary to follow the symptomatic treatment as prescribed by the doctor after clarifying the cause of the disease to slow down the rate of renal progression. When creatinine 147μmol / L, it is recommended to consult the hospital in a timely manner, follow the doctor’s instructions to improve the examination, to clarify the cause of the disease and then symptomatic treatment, so as not to delay the condition.