Gastropathy of Drugs is an adverse reaction of the stomach caused by drugs, accounting for about 1/3 of drug side effects. many oral drugs can cause stomach discomfort, but sometimes they can also cause stomach discomfort such as nausea, vomiting, and loss of appetite even though they are not administered orally. Examination of gastric symptoms during drug administration: Examination and diagnosis of gastric symptoms during drug administration. The main condition for diagnosis is the appearance of gastric symptoms during drug administration, and other causes can be excluded. On fiberoptic gastroscopy, extensive congestion of the gastric mucosa, multiple erosions, bleeding spots, and superficial ulcers are seen. Sometimes active bleeding manifestations were seen in the stomach. The lesions are mostly located in the gastric body, with a few involving the lower esophagus and duodenum. Tissue biopsies of the lesions often show inflammatory cell infiltration, superficial mucosal necrosis, and hemorrhage. The clinical manifestations of drug-related gastroparesis vary depending on the type and dose of medication used and whether it is combined with stimulant gastric drugs. However, the main symptoms are gastric irritation, gastric mucosal barrier damage to varying degrees, and in severe cases, gastric ulceration and bleeding. Fiberoptic gastroscopy: extensive gastric mucosa congestion, multiple erosions, bleeding spots, and superficial ulcers can be seen. Sometimes, active bleeding is seen in the stomach. Tissue biopsy: Inflammatory cell infiltration, superficial mucosal necrosis, and hemorrhage are often present. Prone to gastric ulcer or gastritis, gastrointestinal bleeding, etc. 1.Emergency blood, urine, stool routine, fecal occult blood (blood type should be checked if there is vomiting blood, and gastroscopy should be done within 48 hours). 2, chest X-ray, ultrasound, liver function, electrolytes, blood sugar, lipids, ECG, within 3 days. 3.Gastroscopy review before discharge.