Depression and anxiety disorders are two of the most prevalent mental disorders today. Depression is usually characterized by endless sadness – it is known as the “loner”. Anxiety disorders are characterized by endless anxiety, where the patient feels like entering a different world and is anxious all day long like an ant on a hot pan. Although both anxiety disorders and depression are mental illnesses, there is a big difference between them. The difference between anxiety and depression is divided into the following points: 1. Depression is often accompanied by anxiety symptoms, but depression is mainly depression, and anxiety is often only an emotional reflection of depression, accompanied by other emotional reflections, such as compulsion, suspicion, fear, etc. In the clinic, the symptom scale can be used to test and distinguish the priority of symptoms. 2, patients with anxiety disorders do not have suicidal thoughts, despite the fear, but not yet to die to escape; while patients with depression often have suicidal thoughts or even suicidal behavior. 3, the main emotional expression of anxiety disorder is excessive worry about what may happen in the future and suffering as a result; the dominant emotional component of depression is more complex and includes self-blame, self-guilt, low self-esteem, autism, sensitivity, etc. in addition to the emotional reflection with anxiety characteristics. 4. The somatic symptoms of anxiety disorders are mainly related to the vegetative nerves, such as breathing, heartbeat, sweating, etc., while the somatic symptoms of depression patients have a certain solidity, such as “plum kernel gas”, pain in both sides, heaviness around the body, loss of libido, etc. 5, anxiety disorders because of anxiety also appear to avoid certain things, but not widespread interest and intention to decline; while depression is a wide range of withdrawal and intention to decline. 6.Patients with anxiety disorders are often in a state of distraction, panic and nervousness, fear of woe coming with panic foreboding, and accompanied by dizziness, excessive sweating, hot flashes, tremors, numbness in the hands and feet, gastrointestinal discomfort and other symptoms. Anxiety is different from fear. The threats and dangers felt by anxiety are unrealistic or not very clear. 7, anxiety disorders often coexist with depression, clinical statistics, 80 ％ more than depressed patients have anxiety symptoms. In clinical diagnosis, there is a “depression priority diagnosis” principle, that is, when there are symptoms of depression and anxiety symptoms, regardless of their anxiety symptoms multiple, should be diagnosed as depression. In terms of age of onset, the first onset of anxiety is usually over 35 years old and occurs mostly in older people, while depression occurs in all age groups.