Itchy skin at the bend of the leg may be caused by eczema, atopic dermatitis and pruritus. 1. Eczema: It is caused by the stimulation of many factors inside and outside the body, and the skin at the bend of the leg of the patient may appear edema, erythema, pimples, and accompanied by itching sensation. 2. Atopic dermatitis: the cause of the disease is still unclear, it may be caused by allergic factors, genetic factors, bacterial and other pathogenic bacterial infections, mostly in children and adolescents, mainly manifested in the bend of the leg and the elbow joints of the upper limbs of the obvious itchy symptoms, but also can be accompanied by pimples, erythema and flaking. 3. Pruritus: usually caused by dry skin or leukemia, renal insufficiency and other diseases, usually manifested as itchy skin at the bend of the leg, especially after the patient scratches, secondary rashes such as scratches and so on. There may be other causes of itchy skin in the crook of the leg, and it is recommended that patients actively seek medical attention to clarify the cause of the disease and then carry out regular treatment.