Irbesartan is not recommended to be taken in the morning and evening. 1. Irbesartan is a relatively long half-life antihypertensive drug, which has an end-clearance half-life of 11-15 hours, and its effect can be maintained for about 24 hours after taking it. Therefore, Irbesartan is recommended to be taken once a day, and diet has no effect on the taking of the drug. 2. Irbesartan tablets are available in clinical specifications of 0.075g, 0.15g and 0.3g, and the initial and maintenance dose is usually recommended to be 150mg per day, however, for hemodialysis and patients over 75 years of age, the initial dose may be considered to be 75mg, and the initial dose for hypertensive patients with type 2 diabetes mellitus should be 150mg per day, and the dosage is to be incremented to 300mg. The specific dosage should be taken according to the instructions of the doctor strictly. The exact dosage should be taken in strict accordance with the doctor’s instructions. 3. Adverse reactions: common adverse reactions after taking Irbesartan include dizziness, nausea, vomiting, fatigue, occasional tachycardia, edema, cough, diarrhea, chest pain and so on. 4. Precautions: diabetes or moderate-to-severe renal impairment of patients can not be used in combination with aliskiren, diabetic nephropathy patients can not be used in combination with angiotensin-converting enzyme inhibitors (ACEIs). 5. Contraindications: hypersensitivity to the components of the product, the fourth to ninth month of pregnancy, lactation is prohibited. Irbesartan should be taken under the guidance of a doctor, do not adjust the dose without authorization, if you feel unwell during the medication, please consult a doctor in time.