When a woman is having a hard time with her menstruation, it is usually caused by a drop in hormone levels in the body or by diseases. 1. Generally speaking, the levels of estrogen and progesterone in a woman’s body drop significantly during menstruation, and some women are extremely sensitive to this drop in hormone levels, resulting in nausea, headache, fatigue, abdominal pain, lumbar and knee pain, breast tenderness, and other uncomfortable symptoms. These symptoms are generally normal during menstruation and will be relieved by the end of menstruation. 2. During menstruation, some women’s body resistance will be reduced, and it is very easy to catch a cold, overworked and other reasons leading to colds and other illnesses, which will lead to unpleasant symptoms. If the symptoms are obvious, the patient should consult a doctor in time to determine the cause of these symptoms and take appropriate measures.