1.5. Knee cavity puncture, lavage and intraluminal drug delivery therapy First, knee cavity puncture is performed to confirm that the joint cavity has been entered and joint lavage is performed to cleanse the joint cavity of inflammatory metabolites, and then 2 ml of sodium hyaluronate injection is injected into the knee joint cavity. Prednisolone acetate 2 ml (or Depo-Provera 2 m1) and 0.5% lidocaine 3-5 ml can also be used for injection into the knee cavity. 1.6 Acupuncture and moxibustion therapy 1.6.1. Conventional acupuncture and moxibustion are performed on calf nose, knee eyes, blood sea, Liangqiu, Yanglingquan, Yinlingquan, Foot Sanli, Heigu, Xiexi, Weizhong, and Aye points. For heat-heavy knee joint, we need to add Gaji, Quchi and Hegu; for wet-heavy knee joint, we need to add Sanyinjiao; for qi-stagnation and blood stasis, we need to add Diaphragmatic acupuncture point; we need to use the techniques of lifting and inserting, twisting and twisting, and Canglong swinging tail. 1.6.2. Electro-acupuncture is applied to calf nose, knee eye, blood sea, Liangqiu, Yanglingquan, Yinlingquan, Feosanli, Hegu, Taichong, and Aye points. After obtaining the gas, connect the G6805-2 electro-acupuncture therapy instrument, with continuous wave or sparse wave, the intensity of stimulation is appropriate to tolerate, 1 time / d, 10 times for a course of treatment. 1.6.3, Qi acupuncture method Select the Blood Sea, Liangqiu, Calvary, Knee Eye, Yanglingquan, Yinlingquan, Foot Sanli, Hegu, Xiexi, Weizhong, and Aye points. 1.6.4, warm acupuncture for cold pain in the knee joint can be Warm acupuncture can be used. Take the calf nose, knee eye, blood sea, Liangqiu, Yanglingquan, Yinlingquan, foot Sanli, Heigu, Xiexi, Weizhong, and Aye points, etc., and apply the techniques of lifting and inserting, twisting and turning, and swinging the tail of the dragon. 1.7. Small needle knife stripping of the knee joint The small needle knife is used to perform longitudinal and transverse sparing, shoveling and cutting techniques on the painful area around the knee joint. At the same time, using the acupuncture effect of small needle knife to unblock the meridians and harmonize the qi and blood to achieve the therapeutic purpose of “no pain if you pass”. 1.8, manipulation can correct the bad stress, improve the function of joint capsule and ligament system, stop the development of the disease, and promote the functional healing of joint cartilage. The techniques are based on pressure on acupuncture points and pain points, soft tissue release around the knee, kneading and kneading, and stretching of the joint. The patient is placed in a supine position with the affected knee straight, and the affected leg is kneaded with both hands from the thigh to the ankle 3 to 5 times, then the thumb is used to knead the patella for 3 to 5 min, and the thumb is used to press the points such as Heting, Calvaria, Sansili, Yanglingquan and Blood Sea for 30 s to 1 min. The knee was then rubbed about 30 times in the medial and lateral gaps of the patella and 20 times in flexion. This method 2 times / d, 7 d for a course of treatment.