Babies are usually able to take lactase after oral rotavirus vaccination. Oral rotavirus vaccines include live oral rotavirus vaccine and live oral pentavalent reconstituted rotavirus vaccine. Lactase is a preparation used for intestinal cramps, flatulence, and diarrhea after eating dairy products due to a lack of sugar enzymes. If your baby needs to take lactase because of a sugar deficiency, you can take lactase as normal after the oral rotavirus vaccine and before eating dairy products. Lactase does not affect the effectiveness of the rotavirus vaccine, and it can prevent discomfort caused by lactose intolerance, which is beneficial to your health. Lactase has no known side effects and does not interact with other medications. It is safe for your baby to take lactase when the indications are met. After the oral administration of rotavirus vaccine to babies, parents should closely monitor the health of their babies and consult their physicians if there is any abnormality.