Coffee generally does not cause gout. The main component of coffee is caffeine. The metabolite of caffeine in the human body is urea, which is structurally different from urate, and generally does not lead to gout, but one should pay attention to drinking coffee with low concentration. The pathogenesis of gout is currently unclear, but it is mainly related to elevated blood uric acid levels. It may be induced by impaired uric acid excretion, excessive uric acid production, long-term consumption of foods with high purine content, such as animal offal and seafood and shellfish, long-term consumption of alcohol and drugs that affect uric acid excretion, such as hydrochlorothiazide and ethambutol. Gout should pay attention to early treatment, daily attention to regular follow-up, monitoring the condition changes. It is also necessary to pay attention to increase the intake of fresh vegetables, reduce the intake of greasy and high purine food, maintain a healthy weight, regular exercise. It is recommended that gout patients go to the hospital in a timely manner to avoid delays in their condition.