Fenofibrate and benzofibrate, the two drugs have different indications, the patient’s sensitivity to the drug is also different, the therapeutic effect will be different, there is no so-called “which effect is good”, the specific use of drugs need to follow the doctor’s instructions. Fenofibrate is a lipid-regulating drug, which is more effective than cholesterol in lowering triglycerides and mixed hyperlipidemia, and is mainly used in the treatment of hyperlipidemia in adults who do not have a significant effect of diet-control therapy. Fenofibrate is a lipid-lowering drug with indications for the treatment of hypertriglyceridemia, hypercholesterolemia and mixed hyperlipidemia. Fenofibrate is well absorbed in the gastrointestinal tract after oral administration, and usually the blood concentration can reach the peak in 4-7 hours, and the probability of its adverse reactions is lower, while benzofibrate is rapidly absorbed, close to completely absorbed, and the blood pressure concentration reaches the peak in 2 hours after oral administration, and most of the patients may suffer from adverse reactions after taking it, the most common of which are dyspepsia, anorexia, nausea, and other gastrointestinal discomforts. Fenofibrate and benzofibrate are both prescription drugs, patients should be used under the guidance of a doctor, avoid blind use of drugs to avoid adverse effects.