No antibodies to hepatitis B indicate that one has not been infected with the hepatitis B virus or has not received the hepatitis B vaccine, which is not serious if one is not in a high-risk group. If you are in certain occupations, such as blood-related medical personnel, have a spouse with hepatitis B, or have a history of unclean injections, you need to get the hepatitis B vaccine to prevent being infected with hepatitis B. Currently, newborns receive the hepatitis B vaccine within 24 hours of birth, a second dose of the vaccine one month later, and a third dose six months later. Hepatitis B surface antibodies will gradually decrease in titer over time, and generally after 10 years the hepatitis B surface antibodies may turn negative, so a new hepatitis B vaccination is needed.