Age-related epiphyseal closure generally refers to the closure of the epiphyses of the long bones of the human body, which usually stop growing in height.
The epiphysis represents the cartilage between the epiphysis and the metaphysis. In children or adolescents, the development of height mainly depends on the development of bones in the epiphysis, that is, the epiphysis in the process of bone development in the cartilage at both ends of the bone will appear in the center of ossification, and this continuous ossification will make the height gradually increase.
When the cartilage between the epiphysis and the metaphysis is completely ossified, a tight seam is formed, which indicates that the epiphysis is completely closed, i.e., the bone has reached the age of complete closure. This means that the bones have stopped growing and will not increase in height. In a few people, there may be a slight change in height after epiphyseal closure, which is mainly accomplished by changes in the intervertebral space of the vertebrae in the spine.