When lifestyle improvements are not effective in controlling blood pressure, doctors will prescribe medications to patients. Medications are by far the most effective treatment for high blood pressure. Anti-hypertensive medications are usually taken for a long time, and most patients will take them for life. The general principles of drug therapy are to lower blood pressure steadily and to provide long-term, continuous treatment. Start with a low dose and gradually increase the dose. A combination of two drugs at low doses is better than a single drug at high doses. Do not stop or withdraw the medication suddenly. The drug should be easy to take. The principles of choosing antihypertensive drugs are: good antihypertensive effect, 24-hour stable antihypertensive, once a day, convenient for patients to take, little side effects, easy for patients to adhere to, and can protect patients’ heart, brain, kidney and other target organs. First-line antihypertensive drugs recommended by the World Health Organization 1. diuretics; 2. calcium antagonists (“diphenhydramine” class); 3. angiotensin-converting enzyme inhibitors (“priligy” class); 4. angiotensin II receptor blockers ( “5. b-blockers (“Lor” class); 6. compound preparations (e.g. Hedzia (Crosartan/hydrochlorothiazide)). Misconceptions in the treatment of hypertension 1. estimate the level of blood pressure by self-perception; 2. stop the medication as soon as the blood pressure drops; 3. lower the blood pressure too fast and too low; 4. set the drug trade-off by the price of drugs.