The third vaccine may refer to the new coronavirus vaccine. Adverse reactions include redness, swelling, pain, and itching at the site of vaccination, and a very small percentage of vaccinated persons may experience adverse reactions such as fever, malaise, muscle aches, and drowsiness. After the third vaccination, the most common adverse reactions are similar to those of other vaccinations, i.e., redness, swelling, pain or itching at the site of vaccination, etc., which are mostly due to differences in the nurses’ injection techniques and the size of the type of vaccination needles used. At the same time, due to the injection of liquid, most people are prone to soreness and swelling at the vaccination site. Itching at the vaccination site, etc. occurs because of a stronger peripheral immune response. A very small number of vaccinated people may have fever, fatigue, muscle pain, drowsiness and other symptoms due to weak immunity or other reasons, most of them do not need to be treated and can recover after a few days of rest. Don’t be too tired after vaccination. If there are serious adverse reactions, go to the hospital in time and notify the doctor at the vaccination office at the same time to avoid adverse consequences. Tips] In this article, “new coronary pneumonia, new coronary virus pneumonia” has been renamed to “new coronary virus infection” on December 26, 2022, as announced by the National Health Commission.