After conservative treatment or symptomatic supportive therapy for pancreatitis, the patient develops high blood glucose, due to the large number of pancreatic islets destroyed in the process of pancreatitis, the B-cells in the pancreatic islets are reduced, and the relative insufficiency of insulin secretion will result in pancreatic diabetes mellitus. When the disease is relatively mild, the blood glucose may be gradually reduced to normal through appropriate postoperative adjustments to restore the function of islet B cells. However, in severe cases, including hemorrhagic necrotizing pancreatitis, lifelong diabetes mellitus may develop due to massive necrosis of the pancreas and destruction of pancreatic tissues. For the increase of blood sugar after pancreatitis, it is necessary to adopt a specific glucose-lowering program according to the different conditions, including oral medication, and if necessary, insulin can also be applied to regulate blood sugar.