Diabetic patients with hyperglycemia can cause systemic microangiopathy and in the eye cause retinal microangiopathy and visual dysfunction, called diabetic retinopathy (DR).DR is the most common diabetic microangiopathy.50% of diabetic patients can develop DR about 10 years after the onset of the disease, and 80% of those with more than 15 years. DR occurs later in those with well-controlled blood sugar than in those with poor control. Obesity, smoking, hyperlipidemia, pregnancy, hypertension, and kidney disease can aggravate the glucose network. dr is the main blinding eye disease in people over 50 years old. High blood glucose can damage microvascular cells, causing microvascular dilation, leakage and occlusion, resulting in retinal non-perfusion area, leading to retinal ischemia and hypoxia, in order to cope with ischemia and hypoxia, human tissues will produce “neovascularization” to increase blood supply, but the wall of the produced “neovascularization However, the walls of the generated “neovascularization” are not as intact as the walls of normal blood vessels, which can easily produce leakage and hemorrhage, and since the maintenance of normal retinal tissue function requires a relatively “dry” environment (which can be provided by normal retinal blood vessels), the leakage and hemorrhage of the “neovascularization Because the maintenance of normal retinal tissue function requires a relatively “dry” environment (which normal retinal blood vessels can provide), leakage and hemorrhage from “neovascularization” will inevitably affect the metabolism of retinal tissue and cause visual dysfunction. Another ocular structure that affects the course of the “sugar retina” is the relatively “empty” cavity in front of the retina – the vitreous cavity, which in adults is a transparent, liquefied or incompletely liquefied vitreous cavity. In adults, the vitreous humor is a transparent cavity filled with liquefied or incompletely liquefied vitreous humor. The vitreous cavity is a clear, liquefied or incompletely liquefied cavity in adults. Light from the retina enters and is examined and treated through the vitreous cavity, but the “new blood vessels” on the retinal surface can rupture when pulled by the vitreous and for other reasons, sending bleeding into the vitreous. This makes the light pathway, which should be transparent, cloudy and unclear. Not only is the patient’s vision severely impaired, but the doctor is also unable to see the fundus and, of course, cannot perform fundus laser treatment. This is what this article is all about, and it is the vitreous humor and clouding that is caused by diabetes. According to the progression of the “sugar network”, it can be divided into the non-proliferative phase and the proliferative phase, the non-proliferative phase without “neovascularization”, can be treated with drugs and regular observation, once there is “neovascularization” Once the “neovascularization” appears, it enters the proliferative stage and should be promptly treated with laser, which will coagulate part of the retinal tissue in the ischemic area, reduce the need for oxygen, improve the fundus ischemia, and make the neovascularization subside. Once vitreous blood accumulation occurs, it affects the photocoagulation treatment of the fundus, except for those who have very little bleeding and do not affect laser treatment after absorption, or those who have less bleeding and have photocoagulated the retina below before bleeding, most of them need vitrectomy surgery. The indications for vitrectomy surgery to treat fundus hemorrhage caused by diabetes are mainly: vitreous hemorrhage, proliferative vitreoretinopathy, and retinal detachment. The timing of vitrectomy surgery: In the past, diabetic vitreous hemorrhage was generally treated with medication first, let it be absorbed, and then wait for 3 months without absorption before vitrectomy (there are still many doctors doing this), the fact that diabetic vitreous hemorrhage cannot be completely absorbed, most of them have made the disease progress in the process of waiting for absorption, forming proliferative vitreoretinal lesions, retinal detachment and vascular occlusion, losing the best time for treatment. Now generally in DR vitreous hemorrhage for 2 weeks is not absorbed that should be done biosurgery The reason for the difference between the past and present: the former biosurgery technology is poor, the effect of biosurgery is very poor, but accelerate the patient blindness. After drug treatment, the bleeding was partially absorbed and the patient could maintain poor vision for a period of time. Nowadays, it is possible to achieve complete cure by doing biosurgery early. The effect of late treatment is very poor. The prerequisite is a skilled surgeon and good surgical equipment. The patient should cooperate with the medication and observation.