Degenerative knee disease, also known as osteoarthritis, osteoarthrosis, degenerative joint disease, proliferative arthritis disease, hypertrophic arthritis, and age-related arthritis, is the most common type of chronic, progressive joint disease. Its pathology is characterized by degeneration and destruction of articular cartilage, sclerosis of subchondral bone, reactive hyperplasia of joint edges and subchondral bone, and formation of bone redundancy. Cartilage destruction, wear and tear, loss, and even stiffness of the joint. There is oozing in the joint, edema, deformation of the knee joint, increased speed, etc. The pain can be heavy with activity, reduced with rest, and can still be painful or even worse with re-activity. Difficulty in going up and down stairs, change in walking posture. Treatment, pain relief and anti-inflammatory, joint lubrication, promote cartilage repair, extract exudate, release joint stiffness. Calcium supplementation to reduce osteoporosis. Weight loss to reduce weight bearing on the knee joint. Arthroscopic cleaning of the knee to remove burrs, inflammatory material in the joint cavity and even knee artificial joint prosthesis replacement.