High neonatal bilirubin often indicates jaundice in newborns, which is one of the most common symptoms of the neonatal period, mainly manifesting as yellowing of the face, trunk and whites of the eyes. Most newborns mainly have physiological jaundice, mainly caused by the accumulation of bilirubin in the body, will generally subside on their own, full-term infants generally appear 2-3 days after birth jaundice, 4-5 days to reach a peak, 5-7 days to subside, the general subside time is not more than two weeks, premature infants jaundice subside time is about 3-4 weeks. If jaundice appears early in newborn babies, usually within 24 hours after birth, and progresses relatively quickly, generally spreading to the whole body and limbs, including the palms of the hands and feet, while lasting longer, accompanied by poor mental health, convulsions, screaming and other abnormalities, the possibility of pathological jaundice is considered, and it is necessary to go to the pediatric outpatient clinic of the hospital in a timely manner to improve blood routine, liver function and other related tests to clarify the pathological jaundice The cause of jaundice should be clarified before further treatment. Therefore, when a newborn baby develops jaundice, the first thing to do is to clarify whether it is physiological jaundice or pathological jaundice.