Men taking entecavir are able to have children. Entecavir is an antiviral drug mainly used for the treatment of hepatitis B caused by hepatitis B virus infection, which can inhibit the replication of hepatitis B virus for treatment. Hepatitis B is a contagious disease that can be transmitted through mother-to-child, blood and sexual contact. It is not a hereditary disease and will not pass on the hepatitis B virus to the next generation, so men taking entecavir are able to have children. If a male patient with hepatitis B prepares for pregnancy and has a child, he should pay attention to personal protection after the birth of the child, and the father’s blood or body fluids should avoid contacting the child’s skin and mucous membranes as much as possible, as well as receiving the hepatitis B vaccine on time, so that the child’s body can produce hepatitis B surface antibodies to prevent hepatitis B virus infection. Hepatitis B male patients should go to the hospital for relevant examinations, according to the specific conditions of the individual under the advice of the doctor for treatment and preparation for pregnancy.