The severity of appendicitis depends on the timely and effective treatment and the occurrence of related complications. The most serious case is gangrenous perforation of the appendix, which can lead to infectious shock and can be life-threatening. In addition, complications related to appendicitis can also be life-threatening if not treated promptly and effectively. The main ones are: 1. abdominal abscess, mostly around the appendix, but of course it can also occur in other areas. 2. portal phlebitis, which is caused by infected blood clots reaching the portal vein from the superior mesenteric vein and can result in fever, chills, and abnormal liver function. 3. peritonitis, which can be limited or diffuse, with pressure pain and rebound pain in the abdomen.