Whole abdomen enhanced CT is relatively safe, generally will not produce obvious harm, a few patients may have radiation damage and contrast reaction and other hazards. 1. Radiation damage: CT examination itself, there will be a certain amount of radiation, part of the population is sensitive to radiation, which may cause a decrease in white blood cells; reproductive organs are also more sensitive to radiation, which may cause abnormalities in the condition of reproductive cells, the overall probability of occurrence is relatively low. 2. Reaction to contrast agent: some people may have allergic reaction after injection of contrast agent in the process of CT enhancement, which may cause skin rash and respiratory difficulties, etc. In addition, the contrast agent is metabolized by the kidneys, which may aggravate the burden on the kidneys. Because of the possibility of corresponding harm, it is necessary to avoid doing the relevant examinations during pregnancy, avoid doing the relevant examinations continuously, and the application of metformin itself needs to be discontinued after 48 hours before doing the examination, because the contrast agent can aggravate the accumulation of metformin in the body and increase the risk of lactic acidosis. The specific situation needs to be standardized under the guidance of clinicians.