Patients with uremia have a variety of clinical manifestations: first, early symptoms of the gastrointestinal tract as the early manifestation, may appear nausea, vomiting, loss of appetite, and even abdominal pain and other symptoms of peptic ulcers. Secondly, clinical manifestations of anemia may also appear, such as dizziness and weakness. The decrease in hemoglobin can be seen in routine blood tests, because uremia can lead to a decrease in ketopoietin secretion, and because of digestive symptoms, patients have a poor appetite, which leads to a decrease in the absorption of iron and other hematopoietic materials. Third, patients will have hypertension because patients with renal uremia will have water and sodium retention, oliguria and other such conditions, which will increase blood volume and may activate the RAAS system. Fourth, the patient may develop edema, which may initially appear as oedema of the eyelids or lower extremities, and may be severe as generalized edema, with possible peritoneal or pleural effusions. Fifth, patients may have heart failure such as panic attacks and chest tightness, and some patients may have arrhythmia, and finally, they may have internal environmental disorders such as high potassium, low calcium, high phosphorus, and renal bone disease caused by secondary hyperparathyroidism.