Migraine is a common neurological disorder, and recent studies have shown that migraine is associated with personality, mood and other psychological factors, suggesting that migraine may be a physical and mental disorder. Migraines are frequent, painful, and difficult to heal, and are often accompanied by psychological disorders such as anxiety and depression, which seriously affect the quality of life of patients. Therefore, it is important to assess and intervene in the psychological and social functioning of migraine patients to improve their quality of life. With the transformation of medical model from biomedical model to biosocial model, people pay more and more attention to the impact of diseases on the quality of life. This paper summarizes the mental health status and treatment of migraine patients by analyzing the recent literature, with the aim of focusing on the psychological adjustment of patients in the future clinical treatment, reducing the psychological pressure of patients, guiding migraine patients to form a healthy lifestyle with Chinese and Western medical theories, and improving the quality of life of patients. It is of practical significance to supplement and improve the diagnosis and treatment system of Chinese and Western medicine in migraine prevention and treatment. 1.Domestic and international research on migraine in Western medicine The causes of migraine are complex and the clinical manifestations are diverse, and the pathogenesis of migraine has not been fully elucidated yet. It is generally believed that it is related to genetic, neurological and vascular factors, endocrine factors and immune factors. More and more studies suggest that migraine is strongly related to personality, emotion and other psychological factors. At present, several clinical and epidemiological studies abroad have shown that migraineurs suffer from reduced quality of life, reduced work efficiency and time, and reduced or lost function in all aspects during both headache episodes and intermittent periods. Some studies have shown that the onset of migraine is closely related to the nature of work, sleep status, personality disposition to female menstrual cycle, and family history. As for the nature of work, the prevalence of migraine is the highest among teachers, microcomputer operators and accountants, which may be related to factors such as high brain concentration and mental tension, etc. Since migraine is a psychosomatic disease, its personality characteristics are generally characterized as suspicious and sensitive, stubborn, easily annoyed and introverted. Therefore, it is very important for this kind of patients to carry out rich spare time life, live a regular life, combine work and rest, maintain a good state of mind, try to relieve the tension and pressure at work, and pay attention to professional training and psychological control. In addition, the anxiety and depression of migraine patients were positively correlated with age, disease duration and frequency of attacks, i.e., as age increases, the longer the disease duration and the more frequent the attacks, the proportion of depression and anxiety also increased, but it was not related to gender. In the relationship with EEG, the abnormal rate of EEG increased significantly in patients with concomitant anxiety and depression, indicating that the abnormal EEG has a certain relationship with anxiety and depression. It suggests that the treatment of migraine should pay attention to the treatment of patients’ anxiety and depression in addition to symptom control, which is essential to improve patients’ quality of life and enhance the efficacy. Quality of life is an important aspect in evaluating the physical and mental health of patients with some chronic diseases as well as the effectiveness of various interventions, and it has been paid more and more attention. Various quality of life scales are therefore widely used as an objective indicator of the impact of disease on patients and the effectiveness of treatment. In China, 62 migraine patients were tested with the Eysenck Personality Questionnaire, the Symptom Self-Rating Inventory and the Comprehensive Quality of Life Assessment Questionnaire to investigate the mental health status of migraine patients and their quality of life, and to compare them with normal controls. The overall quality of life of the migraine patients was poorer than that of the normal control group (P<0.01), involving four dimensions: somatic function, psychological function, social function and material life. The overall quality of life of the migraine patients was worse than that of the normal control group (P<0.01). It was also concluded that migraine patients have many aspects of psychological problems and personality changes, and have poor quality of life. Xu Xianping [8] et al. used the Chinese version of the Health Status Scale SF I-36 to conduct a field questionnaire survey on 122 migraine patients and 112 healthy individuals. Results The migraine group scored significantly lower than the control group on eight dimensions, including physical function, physical function, somatic pain, general health, energy, social function, emotional function, and mental health (P<0.01); the factors influencing the physical composite score of migraine patients were headache frequency, headache degree, and education, and the factors influencing the psychological composite score were headache degree, headache frequency, disease duration, and education. It was concluded that the quality of survival of migraine patients is low, and it may help to improve the quality of survival of patients by controlling their influencing factors, such as headache frequency and degree. Currently, the types of medications used in pharmacotherapy include beta-blockers, anticonvulsants, antidepressants, calcium antagonists, nonsteroidal anti-inflammatory drugs, and angiotensin inhibitors. Antidepressants amitriptyline, nortriptyline, doxepin, fluoxetine, and extended-release venlafaxine have been tried for migraine, but several studies have consistently supported medications for migraine prevention. Among the antidepressants amitriptyline is the only effective drug. And tricyclic antidepressants are especially indicated for migraine patients with sleep disorders and depression. A study was conducted to analyze the effect of paroxetine on the quality of life of migraine patients treated with the antidepressant paroxetine, using the SF I-36 questionnaire as a measurement tool. The results showed that paroxetine combined with ciprofloxacin significantly improved the quality of life of migraine patients and was better than that of those treated with ciprofloxacin alone. Psychological intervention therapy is also an effective treatment. The results showed that rational emotional behavior therapy could reduce the number of migraine attacks and lower the migraine efficacy score, and the recent efficacy was similar to that of the drug group. The long-term efficacy is significantly better than that of drug treatment. 2. Research on migraine in Chinese medicine Chinese medicine classifies "migraine" as "head wind", "migraine" and "migraine head wind". The category of "migraine" is "head wind", "migraine headache" and "migraine head wind". As early as in Su Wen? There are records of "head wind" and "brain wind" in the "Treatise on Wind". The name "head wind" was first mentioned in Zhang Zhongjing's "Golden Medical Essentials? The first reference to "head wind" is found in Zhang Zhongjing's book "Jin Medical Essentials? According to Chinese medicine, the etiology and pathogenesis of migraine are external sensation and internal injury. External sensation headache is usually preceded by wind evil, often accompanied by cold, damp and heat evil up to the clear orifices, causing headache due to dense head meridians; internal injury headache is often caused by liver and gallbladder heat, phlegm and dampness, damp-heat blockage and blood stasis blockage. Migraine is one of the diseases of the mind and body, and in Chinese medicine, it belongs to the evidence of internal injury of the seven emotions. Due to excessive "seven emotions" and "seven emotions" causing disease, the imbalance of yin and yang in the human body leads to the dysfunction of the internal organs, and the stagnation of qi, blood, phlegm and fire can cloud the clear orifices and disturb the mind internally, leading to the occurrence of migraine and other psychosomatic diseases. The Nei Jing attaches great importance to the role of psychological treatment, proposing that "the spirit does not enter, the will does not cure, so the disease can not be cured", pointing out that the treatment of emotional and mental illnesses by acupuncture and medicine is not effective, we must take into account the person's psychological state, in order to achieve satisfactory results. "The basic pathogenic mechanism lies in the malfunctioning of the qi mechanism, and Chinese medicine believes that the liver is the main draining body and has the function of regulating the qi mechanism and regulating the emotions, and too much or too little draining of the liver is the source of psychosomatic diseases, so Chinese medicine puts the treatment of the liver in the first place in the treatment of psychosomatic diseases[. Chinese medicine believes that "the brain is the sea of marrow", mainly relying on the liver and kidney essence and blood to moisten, if the mood is not smooth, liver qi stagnation, qi depression into fire, Yang hyperactivity and wind, wind and Yang up to disturb the top, it is easy to develop this disease. The "Discernment of Qi" says: "This disease is not suitable for the depressed qi, and the evil wind attacks the meridian of Shaoyang, thus causing half of the headache." Only when the mind functions normally can the liver, which is the main organ of drainage, blood collection, soul collection and consideration, function normally, and the maintenance of this physiological state depends on the rise of Yang Qi. If liver yang rises without control, liver yang will turn into wind and wind yang will cause spasm and pain in the brain. The Su Wen? Zhang Xichen called this "cerebral congestion headache" and believed that "the qi from the internal organs is ascending but not descending, and the blood injected into the brain from the heart is forced by the ascending qi, thus causing congestion in the brain The blood from the heart to the brain is forced by the rising Qi, thus causing congestion in the brain and making pain and dizziness. According to "Medical Heart Enlightenment", "Migraine headaches with painful outbursts and sharp pains, either left or right, are mostly caused by wind and fire upward disturbance of the liver meridian", because the liver is just victorious and is the master of sparing and discharging, and its nature likes to be organized but is not depressed, so emotional stimulation can easily cause the liver wood wind to move and wind and yang to disturb. Therefore, internal movement of liver wind and upward disturbance of liver yang is an important pathogenesis of this disease. Zhang Daohou and others also believe that the disease is mainly located in the liver and gallbladder, and its basic pathogenesis is that the liver loses its drainage and carries evil upward disturbance, so that the liver and gallbladder meridians on the side of the head are unfavorable and do not pass and cause pain. Migraine can be triggered by mental tension, overexertion, sudden climate change, bright light stimulation, low blood sugar and alcoholic beverages, and female patients tend to have migraine attacks before menstruation. All these causes are related to the derangement of the drainage function of the liver and the abnormal metabolism of qi, blood and fluid. Ren Sufang [18] et al. formulated their own ping liver active drink to treat 120 cases of migraine, 53 cases were cured, 47 cases were effective, 17 cases were effective, and 3 cases were ineffective, with a total effective rate of 97.5%, and the efficacy was better than that of the oral nimodipine control group. Lai Zhirong [19] treated 63 cases of vascular headache with Chaihu Shuhebi San plus reduction, 28 cases were cured, 23 cases were apparently effective, 9 cases were effective, and 3 cases were ineffective, with a total effective rate of 95.24%. In conclusion, migraine is a physical and mental disorder that seriously affects the quality of life of patients and needs to be widely concerned by the whole society. In the diagnosis and treatment of migraine, we should pay attention to psychological guidance, which is of practical significance to alleviate migraine, reduce the number of attacks and improve the quality of life!