Blisters on the hands may be caused by herpes sweat, eczema, shingles and so on, as follows: 1. Herpes sweat: herpes sweat, also known as dyshidrotic eczema, due to allergies, ultraviolet radiation, dermatophyte infections, etc., hand sweating can not be normally discharged from the body, resulting in fluid retention, the typical symptom of small blisters, often accompanied by intense itching. 2. Eczema: due to genetic factors, immune abnormalities, hormone level changes, etc., in the early stages of the disease will appear red spots, followed by the gradual formation of blisters or pimples, there will be blisters on the hands of symptoms, often accompanied by itching. 3. Herpes zoster: As the body is infected by the herpes zoster virus, resulting in the emergence of an infectious disease that affects the nerves and skin, the hands may also appear lesions, mainly manifested as blisters distributed along the nerves, accompanied by symptoms of pain. It is recommended that patients seek timely medical attention to confirm the cause of the disease after a systematic examination and actively receive treatment.