Do the new crown nucleic acid have to do the nose have to do the mouth, because the collection site is different, respectively, nasopharyngeal swabs, oropharyngeal swabs. 1. Nasopharyngeal swab: Nasopharyngeal swab is sampling personnel will stick the swab into the nostrils, to reach the back wall of the nasopharyngeal cavity, gently rotate for a week, such as physiological coughing, sneezing, need to stay for a few moments, and then gently take out of the seal to send to the test. 2. Oropharyngeal swab: Oropharyngeal swab is sampling personnel will be over the tongue root, in the collected pharyngeal tonsils on both sides of the posterior wall of the pharynx, back and forth several times, sealed and sent for testing. Whether nasopharyngeal swab or oropharyngeal swab can be effective in collecting samples, two hours before the nucleic acid test to avoid eating, so as to avoid vomiting, sampling process, such as irritating dry cough, vomiting and other symptoms, with the collection of personnel relaxation and deep breathing.