Nowadays, due to the increasing incidence of diabetes mellitus in our population, diabetic dermatosis, a complication caused by diabetes mellitus, has become more and more common among diabetic patients. According to clinical research statistics, about 50% of normal people with diabetes may develop different degrees and types of skin lesions. In general, we refer to the various skin-related lesions caused by diabetes mellitus in diabetic patients as diabetic dermatosis. Therefore, learning and understanding about diabetic dermatosis is essential for diabetic patients to actively prevent the development of skin diseases. First, let’s get to know our skin tissue. Skin is an organ with abundant blood vessels, wide distribution of nerves and active metabolism, which participates in and depends on all the metabolic processes of the body, and is the largest organ of the human body, with the functions of protecting the body, sweating, sensing hot and cold pressures and pains, and it is the first natural immunity barrier of the body to defend against invasion of external pathogens. When a normal person suffers from diabetes, our normal skin tissue structure and function has undergone a series of pathological changes. The pathogenesis of diabetic dermatosis is complex, and can be caused by microangiopathy, neuropathy, metabolic disorders, skin surface biochemical reactions and other factors alone or in interaction. Common diabetic dermatoses mainly include skin bacterial and fungal infections, rash, skin pigmentation spots, progressive necrosis of skin lipoid, herpetic dermatosis, diabetic cutaneous xanthomas, diabetic cutaneous neuropathies and so on. The clinical manifestations of diabetic dermatosis are also diverse, mainly manifesting as itching, absence of sweating, rash, blisters, skin pigmentation abnormalities, sensory abnormalities, and even skin gangrene. Due to the complexity of the mechanism of diabetic dermatosis and its various manifestations, it is very important for diabetic patients to have early self-discovery and control management, and it is also very important to learn about diabetic dermatosis in order to prevent and treat it. Diabetic dermatosis treatment principles: diabetic dermatosis is closely related to high blood sugar, so the key to treatment must be actively control blood sugar at the basic level as a prerequisite, and at the same time pay attention to local treatment, combined with systemic medication when necessary. 1.Treatment of primary disease: reduce the concentration of blood glucose, regular monitoring of blood glucose, control blood glucose level. 2.General treatment: pay attention to personal hygiene, reasonable diet, appropriate exercise, mood regulation. On the basis of controlling blood sugar level, early detection of skin lesions and early treatment. For the elderly and people with dry skin, it is enough to take a bath 1 or 2 times a week in winter, and try not to take a bath for more than 15 minutes in summer. Too frequent bathing will cause their skin to become drier and drier, thus aggravating the symptoms of scratching. In normal life, try to avoid all kinds of external stimuli, such as hot water scalding, excessive scratching; do not use public towels, footbaths, slippers and other daily necessities; try to wear loose-fitting clothes and shoes and socks, to prevent affecting the blood circulation of the skin. If there are skin breaks and ulcers, do not treat them by yourself, but go to a regular hospital for examination and treatment. ①Reasonable choice of cleanser and shower gel, try to avoid the use of too strong cleaning power of the bath products. ② Choose appropriate cosmetics or skin care products, minimize skin irritation and gentle moisturizing. ③Pay attention to sun protection, according to their own conditions, control the daily diet and water intake within a reasonable range. ④ If there is any skin lesion or disease, go to the hospital in time. 3, local and systemic drug therapy: according to the different parts of the disease and lesion manifestations, were used to smear, wet compresses, soak, sitz bath, bath and other methods of symptomatic treatment. After sterilizing the skin for bacterial and fungal infections, antibacterial and antimicrobial treatments are used according to the type of lesions and skin condition. If there are blisters, puncture and fluid extraction can be chosen according to the situation; if there are abscesses, incision and drainage of pus can be considered; if there are necrotic tissues, debridement and removal of necrotic tissues are needed. Eczema, itching can be considered oral antihistamine drugs, local topical glucocorticoid cream. Systemic treatment is based on the patient’s condition to choose the appropriate intravenous drug treatment, so as to improve the patient’s general condition.