There are various reasons for numbness of the big toe, and the common causes are inappropriate shoes, peripheral neuropathy, such as multiple peripheral neuritis; lumbar and cervical spine diseases, such as lumbar disc herniation and other factors. 1. Inappropriate shoes: When the patient wears inappropriate shoes, the big toe is squeezed for a long time, resulting in poor local blood circulation, which may lead to symptoms of numbness in the big toe. 2. Peripheral neuropathy: When patients suffer from peripheral neuropathy such as multiple peripheral neuritis, diabetic foot, Guillain-Barre syndrome, etc., it may cause sensory abnormalities such as pins and needles and numbness in the big toe. 3. Lumbar spine and cervical spine diseases: When patients suffer from lumbar disc herniation and cervical spine disease, they may compress the nerve roots, resulting in sensory disorders in the lower limbs, and there may be numbness and weakness in the bunion when it is involved. In addition, cold, rheumatoid arthritis, gout and other factors may also cause numbness of the big toe, it is recommended that patients seek medical examination in a timely manner to clarify the cause of the disease and then targeted treatment.