Women with a lump in the perianal folds can be considered to be associated with external hemorrhoids, rectal polyps, acromegaly or anal papilloma prolapse and other diseases. 1. hemorrhoids: such as external hemorrhoids, in long-term sitting, pregnancy, constipation and other reasons can be induced perianal venous plexus expansion, blood stasis, the appearance of external hemorrhoids, can be seen in the perianal folds of connective tissue external hemorrhoids that is, dermatomes or inflammatory external hemorrhoids. 2. Rectal polyps: polyps can be formed in the rectum due to inflammatory stimuli, and when a low polyp with a tip is prolapsed outside the anus, a rounded pimple can be seen in the perianal folds. 3. Condyloma acuminatum: mainly through sexual transmission, can be seen in the rectum, anus, vulva and other places of the red pimples, with the pimples increase in size, can be changed to cabbage pattern, papillae and other forms, the surface can form erosion. 4. Anal papilloma: the anal canal of the anal papilla long-term inflammation, feces, or trauma, hemorrhoids stimulation, causing inflammatory hyperplasia, hypertrophy to form anal papilloma-like changes, with the discharge of stool, with the tip of the anal papilloma will be out of the anus, the phenomenon of a lump in the perianal folds. Women with unexplained perianal pimples are advised to consult a doctor in time to clarify the nature of the pimples, and then treat the cause and symptoms to avoid delaying the condition.