Acne is generally referred to as acne, which is usually caused by excessive sebum secretion, abnormal keratinization of hair follicle openings, and inflammatory reactions. 1. Excessive sebum secretion: If the patient’s body androgen level is too high, it may lead to sebaceous glands functioning vigorously, increasing sebum secretion and inducing acne. 2. Abnormal keratinization of perifollicular cells: Abnormal keratinization of perifollicular cells may lead to smaller, narrower or even blocked follicle openings on the face of the patient, which prevents sebum from being discharged smoothly and induces acne. 3. Inflammatory reaction: If the over proliferation of acidophilus bacteria in facial acne leads to an inflammatory reaction in the hair follicle area, acne will be easily induced, resulting in localized pimples and itching. In addition, frequent staying up late and eating spicy and stimulating foods can also trigger or aggravate acne, and patients are advised to go to the hospital and follow the doctor’s instructions for treatment.