After drinking coffee stomach discomfort, want to vomit, often related to gastric mucosa stimulation, but do not exclude improper diet and other factors, according to the cause of targeted treatment. 1, gastric mucosa stimulation: coffee is a stimulating drink, a one-time drink more coffee, the gastrointestinal mucosa will produce a certain irritation, easy to cause abdominal discomfort, nausea, vomiting symptoms, some patients may even appear abdominal pain, bloating, diarrhea, etc.. Therefore, patients with weak gastrointestinal function, daily should drink less or no coffee, strong tea, carbonated stimulating drinks, daily drink warm water can be; 2, improper diet: patients who usually eat irregularly, causing gastrointestinal disorders, may also lead to drink coffee after the stomach discomfort, want to vomit. It is recommended to regulate dietary habits, eat light, easy to digest food, less spicy and stimulating, cold, hard food, avoid overeating; 3, acute gastroenteritis: drinking coffee-based stimulating drinks or coffee contaminated with bacteria, triggering acute gastroenteritis, will lead to stomach discomfort, nausea, vomiting symptoms, the symptoms are mild can be used under the guidance of a doctor omeprazole, mosapride to protect the gastric mucosa and relieve discomfort If there is bacterial infection, anti-infection treatment with drugs such as gatifloxacin, moxifloxacin and levofloxacin can be applied.