The maintenance time of stem cell filling varies somewhat depending on the transplant site, individual body type, and the activity of stem cells after filling. Stem cells are the most primitive cells in the body, a kind of pluripotent cells that can differentiate into various tissues and organs of the body, etc. They are also the key to maintain the growth of fat cells. Most of the aging of the body is due to the atrophy of fat cells, when stem cells can be used to fill the desired area to improve the aging of that area. Clinically, stem cell filler is mostly used for facial wrinkle removal. If the survival rate of stem cells after filling is high, it can generally last about 5 years; if the survival rate of stem cells after filling is low, it may only last about 1 year. It is recommended to go to the plastic surgery department of regular hospitals for stem cell filling to avoid complications such as vascular embolism, tissue necrosis and tissue asymmetry.