Pressure urticaria should first be treated by removing the triggering factors and then by using topical and oral medications. Pressure urticaria may be related to allergies, low immunity, infections and other factors, manifested as stripes and raised winds in the skin of the pressurized area. 1. Remove the triggering factors: Pressure urticaria first need to remove the triggering factors, pay attention to the observation of allergens, such as a certain kind of food or drugs, once found immediately stop using. It is also necessary to reduce the pressure, such as do not carry heavy objects for a long time, long standing or continuous sitting, etc., may aggravate the symptoms, when the removal of triggering factors, the symptoms will have a certain degree of relief. 2. Topical medication: local topical anti-itch lotion, such as glycerite lotion, etc., can also be used externally with glucocorticoid creams, such as mometasone furoate cream, halometasone cream. 3. Oral drugs: severe symptoms can be combined with the application of oral drugs, such as loratadine tablets, cetirizine hydrochloride tablets, etc., if the therapeutic effect is not good, can also be oral glucocorticoid drugs, such as prednisone tablets, dexamethasone tablets. All of the above drugs have adverse reactions and are recommended to be used under the guidance of a doctor. During the treatment period, take the medication as prescribed by the doctor, and pay attention to wear loose clothing as much as possible, keep enough sleep and a good state of mind, which is conducive to the recovery of the disease.