Muscle twitching under the mouth may be caused by agitated tension state, cold, facial muscle spasm and so on. Attention should be paid to relieving emotions, keeping warm and timely symptomatic treatment. 1. Excitement and nervousness: When people are excited and nervous, the sympathetic nerves are abnormally excited due to autonomic nerve disorders, which will lead to muscle twitching under the mouth. At this time, patients should pay attention to ease their emotions and maintain a good state of mind. 2. Cold: Cold easily leads to muscle spasms around the lips, resulting in the symptoms of twitching of the muscles under the mouth. At this time, patients should pay attention to get out of the cold environment, pay attention to keep warm. 3. Facial muscle spasm: also known as facial muscle twitching, manifested as involuntary twitching of one side of the facial muscles, twitching paroxysmal and irregular. It is necessary to pay attention to avoid local stimulation, such as acupuncture, electrotherapy, etc., to avoid aggravating the symptoms. If the patient has the symptom of muscle twitching under the mouth, he should also pay attention to prohibit smoking and alcohol, and keep away from spicy and stimulating food. If the patient’s symptoms do not improve through the above methods, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor, improve the relevant examination, to clarify the cause of the disease, symptomatic treatment.