Babies with a little runny nose should not be vaccinated, so as not to cause adverse reactions. Vaccine itself is attenuated or inactivated pathogenic microorganisms, belonging to the foreign stimulus material, the body will react after injection, can be divided into local reaction and systemic reaction, local reaction manifested as red, swelling, heat, pain at the injection site, systemic reaction can be manifested as fever. The baby’s runny nose is a manifestation of a cold, in which case the body’s resistance will be lowered, and at this time the injection of the vaccine is more likely to have side effects, which will also easily affect the effectiveness of the vaccine, in order to avoid the loss, the baby’s body can be recovered before the vaccination. It is recommended to wait until a week after the symptoms of the cold subside, no other symptoms before vaccination, so as to avoid unnecessary harm to the baby. Avoid bathing and eat a light diet within three days of vaccination. If the baby is breastfed, the mother should not eat spicy and stimulating food.