Painful urination with bleeding is mainly considered to be related to external injuries, inflammation of the urinary system, urinary stones and tumors of the urinary system. 1. external injury: the lower body has been hit by external forces, which can lead to local soft tissue damage, capillary rupture, and then appear painful urination, bleeding and other symptoms. 2. Inflammation of the urinary system: such as urethritis, cystitis and other diseases, which can lead to symptoms of urinary pain, some patients with serious conditions, there can be urethral mucosal breakage, and then bleeding symptoms. 3. urinary stones: such as bladder stones, kidney stones and other diseases, some large stones in the urinary tract with the urine into the urethra, may scratch the urethra, and then appear urinary pain, bleeding and other symptoms. 4. Tumor of urinary system: such as urethral cancer and other diseases, with the increase of tumor, it will cause pressure on urethra, and then new symptoms such as painful urination, frequent urination, difficult urination and bleeding will occur. If the above symptoms appear, you should pay enough attention to them, consult doctor as soon as possible to confirm the diagnosis, and follow the doctor’s instruction for treatment.