What drugs to take to reduce swelling fastest, depends on what the swelling is, a situation is edema, due to a variety of reasons caused by the accumulation of fluid in the body or water gathered to the subcutaneous tissue caused by, called edema. If it is edema to reduce swelling, you need to use diuretics, the use of diuretics can diuretic swelling. Another situation is due to a variety of inflammation, injury and external toxic substances caused by swelling, is a kind of inflammation infiltration, common such as arthritis will also appear swelling, as well as cellulitis, mosquito bites and so on. This is a time for specific treatment depending on the situation. In the case of arthritis, medications to reduce swelling and pain as well as non-steroidal painkillers should be taken. If it is cellulitis, may also need to use antibiotics for anti-infection treatment, different situations to be treated differently, there is no fastest only more appropriate.