The biological clock regulates vital functions of the body, such as behavior, hormone levels, sleep, body temperature and metabolism …… The results of this Nobel Prize study suggest that when our lifestyle is always against our body’s internal “timer”, the risk of developing The risk of various diseases is likely to increase. To sum it up: don’t stay up late, get up at the right time! The dangers of staying up late 1, disfigurement and ugliness According to a report by the London Sleep School, reducing sleep by two hours a day for a week or less can have a serious impact on appearance. The number of fine lines and wrinkles among the women who participated in the survey rose by 45%, and the number of spots rose by 13%. People’s eyes become red and puffy, the skin becomes loose and saggy, and more wrinkles grow. 2. Alopecia areata is a kind of autoimmune non-scarring hair loss, commonly known as “ghost shaving”. The hair falls out unconsciously and is often discovered unintentionally or by others. The main cause of baldness is emotional, but anxiety and shock may also cause baldness. Staying up late at night may cause endocrine disruption, which can also cause baldness. 3. Sudden deafness Sudden deafness is when you can’t hear all of a sudden when you were fine. Frequent late nights, long-term fatigue, and lack of sleep can hinder the blood supply to the inner ear, which can easily lead to sudden deafness once it is stimulated by external factors (such as sudden temperature changes and viral infections). 4, damage to the eyes The damage to the eyes from staying up late is not just a simple matter of having “panda eyes”. Long-term eye overload will cause pain, dryness and other problems in the eyes, and even make people suffer from dry eye disease; long-term overwork caused by staying up late may also induce central retinitis, resulting in a sudden drop in vision. 5, neurasthenia, headache insomnia after staying up late the next day, the sympathetic nerve is difficult to fully excited, will make people no spirit, dizziness, memory loss, inattention, slow reaction, forgetfulness and dizziness, headache, etc.. Over time, there will be neurasthenia, insomnia and other more serious problems. 6, Alzheimer’s disease A recent study by scientists showed that when rats do not get enough sleep, it makes the brain show bad omens and may trigger Alzheimer’s disease (dementia). 7, hypertension, sudden death Studies have shown that chronic sleep deprivation is an important causative factor for hypertension, which also makes late night people suffer from all kinds of sudden cardiovascular disease, the chances of a great increase in serious will lead to sudden death. 8, diabetes For people with a family history of diabetes, staying up late often increases the chances of developing diabetes. Compared to others, people with a family history of diabetes have certain triggers for the disease, and if the conditions are right, like a seed meeting the right environment, it will soon take root and sprout. 9. Cancer Medical research shows that people who stay up late are more likely to develop cancer than those who sleep normally. Take pancreatic cancer as an example, the incidence rate of people who stay up late often is more than three times higher than the average person. This is because cancer cells are produced during the process of cell division, which mostly takes place during sleep. Staying up late will affect the normal division of cells, which will lead to cell mutation and produce cancer cells. 10, immune dysfunction Staying up late for a long time will lead to dysfunction of the body’s immune function, which will be manifested in the kidneys and produce nephritis; in the skin, it may be lupus erythematosus; in the joints, it is rheumatoid arthritis …… the body is in a subhealthy state, respiratory diseases such as colds and flu, gastroenteritis and other digestive diseases will come to the door.